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What are Spore-forming Probiotics?

bacillus spore

Probiotic bacteria need to be alive when they reach your gut. So they must survive things like manufacturing or preparation processes (baking, boiling, etc.) AND survive the transit to your gut; otherwise you will not receive any benefits.

But what probiotics are the best to get the benefits you want most? First, it’s helpful to understand the most common probiotic types. There are three genera of bacteria that comprise most bacteria with recognized probiotic activity: Lactobacillus, Bifidobacteria and Bacillus.

Lactobacillus and Bifidobacteria are Common Vegetative Bacteria

Strains of Lactobacillus and Bifidobacterium are supplied in their living, vegetative states. That is, they are living organisms that require very specific environments to remain viable. Often found in fermented dairy products, these typically cannot be used in products that are shelf-stable, frozen, heated, or subjected to extreme manufacturing processes.

Also, their cells are not particularly resistant to high heat and tend to be sensitive to the extremes of acid and alkaline conditions, as found in the stomach and small bowel. For example, studies have shown that most are quickly killed off in the harsh, acidic environment of the stomach and upper digestive tract. And because these bacteria are fragile, they require refrigeration to remain viable.

Lactobacillus or Bifidobacterium are Vegetative Bacteria and are:

  • Very fragile, making it harder to get them to your gut
  • Susceptible to damage from most harsh manufacturing and preparation processes
  • Generally, in need of refrigeration, making it more difficult for product makers to create a range of probiotic foods and beverages

list of differences between spore forming and vegetative probiotics

Get More with the Spore

Bacillus, by contrast, are hardy, spore-forming bacteria that act as vegetative bacteria when conditions are optimal for their growth but can also form dormant spores when conditions are detrimental to their viability. This spore can be equated to a plant seed—it is dormant and won’t grow until there is the right temperature, moisture and food source.

Research on specific Bacillus strains has shown they can withstand both heat and acidic conditions, and these spores are much more resistant to the extremes of pH, heat, cold and pressure than vegetative cells. This makes them a much better fit for fortification in everyday foods and beverages, such as products that may be hot, cold or frozen, shelf-stable, or subject to extreme manufacturing processes.

GanedenBC30 is a Spore-former and:

  • Has a naturally protective outer layer makes them highly stable
  • Can survive most manufacturing and preparation processes
  • Survives the low pH of the stomach
  • Can be used in a wider range of foods and beverages, giving you the digestive and immune health benefits you want most

GanedenBC30®, a Natural, Spore-forming Probiotic Ingredient

GanedenBC30® (Bacillus coagulans GBI-30, 6086) is a safe and efficacious spore-forming probiotic ingredient with research-backed health benefits. GanedenBC30 has a protective shell so it can survive extreme temperatures like hot and cold, microwaves and boiling water. This makes it easier for food and beverage makers to create food and beverage products with GanedenBC30, so you can have unlimited ways to get your probiotic throughout your day.

GanedenBC30 can also survive through your stomach acid until it arrives in your gut, where it teams up with your own bacteria, providing you with the digestive health, immune health and protein utilization benefits you want most.


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